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Synthesis Of 2-Styryl Derivatives of N, N-Bis-Substituted Quinazolines

Author

Listed:
  • Harutyunyan Artur A

    (Russian Armenian (Slavonic) University, Armenia, Asia)

  • Ghukasyan Gohar T
  • Danagulyan Gevorg G

    (Scientific and technological center of organic and pharmaceutical chemistry, Russian Armenian (Slavonic) University, Armenia, Asia)

Abstract

Interest in the heterocyclic quinazoline system is largely due to the high biological activity that they exhibit, including anti protozoic, anti-inflammatory, sedative, antibacterial, as well as the ability to inhibit kinases, the aurora-serine/threonine kinase involved in the regulation of cell division [1]. In recent works, attention has been drawn to the substituted 2-styrylquinazolines, showing antibacterial, fungicidal and cytotoxic properties [2] and bis-quinazolines - inhibitors of the epidermal growth factor receptor (EGFR) [3].

Suggested Citation

  • Harutyunyan Artur A & Ghukasyan Gohar T & Danagulyan Gevorg G, 2018. "Synthesis Of 2-Styryl Derivatives of N, N-Bis-Substituted Quinazolines," Organic & Medicinal Chemistry International Journal, Juniper Publishers Inc., vol. 7(3), pages 114-114, August.
    • Handle: RePEc:adp:jomcij:v:7:y:2018:i:3:p:114-114
    DOI: 10.19080/OMCIJ.2018.07.555718
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