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Antibacterial Activity of a Triterpene Isolated from Combretum Erythrophyllum Ethyl Acetate Fraction

Author

Listed:
  • F Mtunzi
  • I Ledwaba
  • E Dikio
  • P Ejidike
  • V Pakade

    (Department of Chemistry, Vaal University of Technology, South Africa)

  • M Klink

    (Department of Biotechnology, Vaal University of Technology, South Africa)

Abstract

Combretum erythrophyllum is a member of Combretaceae family, widely used for treatment of venereal diseases. Roots are used as a purgative while dried and powdered gum can be applied to sores. Antibacterial activity of the leaves was investigated against Staphylococcus aureus, Escherichia coli, Enterococcus faecalis and Pseudomonas aeruginosa. Activity guided fractionation of the extracts resulted in the isolation of triterpenoid friedelin from acetone crude extract.

Suggested Citation

  • F Mtunzi & I Ledwaba & E Dikio & P Ejidike & V Pakade & M Klink, 2017. "Antibacterial Activity of a Triterpene Isolated from Combretum Erythrophyllum Ethyl Acetate Fraction," Organic & Medicinal Chemistry International Journal, Juniper Publishers Inc., vol. 4(3), pages 60-65, November.
    • Handle: RePEc:adp:jomcij:v:4:y:2017:i:3:p:60-65
    DOI: 10.19080/OMCIJ.2017.04.555640
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