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Synthesis, Characterization and Biological Evaluation of Copper (ii) Metal Complex with 1,10-Phenanthroline

Author

Listed:
  • Akbar Ali Thebo

    (National Center for Nanoscience and Technology (NCNST), Chinese Academy of Sciences (CAS), China)

  • Noor Ahmad Nahyoon

    (School of Environmental Science & Technology, Dalian University of Technology, China)

  • Shah Nawaz Phulpoto

    (College of Material Science & Engineering, Beijing University of Chemical Technology, China)

  • Azim Khan
  • Sohail Ahmad Shah
  • Sajjad Ali
  • Khalid H Thebo

    (Institute of Metal Research, Chinese Academy of Science, China)

Abstract

Novel copper(II) complex, [Cu(phen)2(OH2)(NO3)2] (1) (where phen = 1,10-phenanthroline) have been synthesized and characterized by elemental analysis, FTIR, EPR, thermo gravimetric analysis, X-ray crystallography and biological activity. Crystal structure determination reveals that complexes (1) possess a neutral monomeric structure. In complex (1), five atoms (N and O) are coordinated with copper (II) ion to form distorted square pyramid structure. Amongst five coordinating atoms, four are nitrogen atoms from two 1,10-phenanthroline moities and one oxygen atom. The thermal decomposition of the complex (1) under an inert atmosphere has also been studied. Furthermore the complex (1) was screened for their anti-microbial activity, and antifungal cytotoxicity. Antibacterial and antifungal results indicate that the metal complexes are more active than the ligand.

Suggested Citation

  • Akbar Ali Thebo & Noor Ahmad Nahyoon & Shah Nawaz Phulpoto & Azim Khan & Sohail Ahmad Shah & Sajjad Ali & Khalid H Thebo, 2017. "Synthesis, Characterization and Biological Evaluation of Copper (ii) Metal Complex with 1,10-Phenanthroline," Organic & Medicinal Chemistry International Journal, Juniper Publishers Inc., vol. 2(1), pages 8-12, March.
    • Handle: RePEc:adp:jomcij:v:2:y:2017:i:1:p:8-12
    DOI: 10.19080/OMCIJ.2017.02.555578
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