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Emerging Applications of Synchrotron-Generated Microbeams in Neurological and Neurosurgical Research

Author

Listed:
  • Pantaleo Romanelli

    (Cyberknife Center,Centro Diagnostico Italiano(CDI) , Italy)

  • Alberto Bravin

    (European Synchrotron Radiation Facility (ESRF), France)

  • Giuseppe Battaglia

    (IRCCS Neuromed, Italy)

Abstract

Recent research performed at ESRF has shown that microbeams arrays delivering incident doses from 300 to 600 GY generate the equivalent of a microsurgical incision over the cortex and hippocampus. These microbeam incisions generate no neurological deficit when delivered to eloquent cortex, offering an attractive new way to treat seizures originating from brain regions not amenable to surgical resection and to modulate neural networks involved in a wide variety of functional brain disorders

Suggested Citation

  • Pantaleo Romanelli & Alberto Bravin & Giuseppe Battaglia, 2018. "Emerging Applications of Synchrotron-Generated Microbeams in Neurological and Neurosurgical Research," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 9(3), pages 55-57, October.
    • Handle: RePEc:adp:joajnn:v:9:y:2018:i:3:p:55-57
    DOI: 10.19080/OAJNN.2018.09.555761
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    References listed on IDEAS

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    1. Pantaleo Romanelli & Erminia Fardone & Giuseppe Battaglia & Elke Bräuer-Krisch & Yolanda Prezado & Herwig Requardt & Geraldine Le Duc & Christian Nemoz & David J Anschel & Jenny Spiga & Alberto Bravin, 2013. "Synchrotron-Generated Microbeam Sensorimotor Cortex Transections Induce Seizure Control without Disruption of Neurological Functions," PLOS ONE, Public Library of Science, vol. 8(1), pages 1-8, January.
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