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Mifepristone and Protection of Purkinje Neurons

Author

Listed:
  • Abdel Moumen Ghoumari

    (Inserm University Paris Sud, Kremlin Bicêtre, France)

Abstract

Mifepristone (RU486) is a synthetic steroid. By binding to the corresponding receptors, it is opposed to the activity of progesterone and gluco corticosteroids [1]. The discovery of the RU486 in the early 1980s made it possible to be used in the early voluntary terminations of pregnancy. Since this date, this molecule has not ceased to raise controversies because of its use for the abortion. Although the RU486 is widely used in USA, Canada, Europe, China, India, South Africa, etc, clinical research has not being developed without difficulty of marketing. The FDA, in September 2000, legalized its use in the United States, based on its efficacy and very good tolerance. The use of mifepristone for early abortion has become more common in the United States during the past 15 years, based on cumulative evidence indicating it safety and effectiveness [2,3].

Suggested Citation

  • Abdel Moumen Ghoumari, 2017. "Mifepristone and Protection of Purkinje Neurons," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 5(2), pages 20-22, July.
    • Handle: RePEc:adp:joajnn:v:5:y:2017:i:2:p:20-22
    DOI: 10.19080/OAJNN.2017.05.555657
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