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Amyotrophic Lateral Sclerosis

Author

Listed:
  • Aymeé Hernández

    (Clinical Neurophysiology Department, Cuban Neuroscience Center, Cuba)

Abstract

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder of unknown cause. More of 400.000 persons are affected by ALS at world level. It is characterized by diffuse involvement of cortical, bulbar and spinal motor neurons. Physiopathology is very complex, there are a lot of changes into the neurons and glia that cause apoptosis and cellular degeneration. The diagnostic of this disorder is based in demonstrating of abnormalities of upper and lower motor neurons. It is based in neurophysiological studies and clinical signs, it is supported by Scorial criteria. New images methods could diagnosis and prognosis evolution of ALS patients and this methods show some important structural and functional abnormalities in nervous structures.

Suggested Citation

  • Aymeé Hernández, 2017. "Amyotrophic Lateral Sclerosis," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 3(2), pages 25-26, April.
    • Handle: RePEc:adp:joajnn:v:3:y:2017:i:2:p:25-26
    DOI: 10.19080/OAJNN.2017.03.555609
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