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Development of an Empty Sella in Neurosarcoidosis

Author

Listed:
  • Arshpreet Kaur
  • Stephen J Winters

    (Division of Endocrinology, Metabolism and Diabetes, University of Louisville, USA)

  • Pankaj Sharma
  • Zeng Wang

    (Department of Neurology, University of Louisville, USA)

  • Charles E Moore

    (Division of Rheumatology, University of Louisville, USA)

  • Mary Koutourousiou

    (Department of Neurosurgery, University of Louisville, USA)

  • Aly Abayazeed
  • Robert Bert

    (Department of Radiology, University of Louisville, USA)

Abstract

We report the case of a 56 year old African American woman who presented with headache, difficulty walking and loss of hearing and vision who had undiagnosed diabetes insipidus and pan-hypopituitarism. MRI revealed inflammation of the meninges with thickening of the pituitary-infundibulum and hypothalamus with spread to the optic chiasm and optic nerves. Dura biopsy confirmed the clinical diagnosis of isolated neurosarcoidosis. During 8 months of treatment with prednisone and methotrexate, there was partial resolution of the dura thickening but the neurological manifestations and the endocrine disorder were unaffected. Swelling of the pituitary became an empty sella.

Suggested Citation

  • Arshpreet Kaur & Stephen J Winters & Pankaj Sharma & Zeng Wang & Charles E Moore & Mary Koutourousiou & Aly Abayazeed & Robert Bert, 2017. "Development of an Empty Sella in Neurosarcoidosis," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 3(1), pages 13-15, March.
    • Handle: RePEc:adp:joajnn:v:3:y:2017:i:1:p:13-15
    DOI: 10.19080/OAJNN.2017.03.555605
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