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Psychological Symptoms in Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS): A Case Report

Author

Listed:
  • Katarina Matic
  • Vladimir Grosic
  • Anamarija Bogovic
  • Igor Filipcic

    (Department of Integrative Psychiatry, Psychiatric hospital, Croatia)

Abstract

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a inflammatory central nervous system (CNS) disorder, prominently involving the brainstem and in particular the pons, characterized by perivascular pathologic reaction lymphocyte infiltration, leading to dysarthria, ataxia, diplopia, altered sensation and paraesthesias of the face, dizziness, nystagmus, spastic paraparesis as well different psychological symptoms. The radiological distribution is focused in the pons and adjacent rhombencephalic structures such as the cerebellar peduncles, cerebellum, medulla and the midbrain [1]. Diagnosis of CLIPPERS is challenging, and requires careful exclusion of alternative diagnoses. Pathogenesis of CLIPPERS remains poorly understood, and the nosological position of CLIPPERS has still to be established.

Suggested Citation

  • Katarina Matic & Vladimir Grosic & Anamarija Bogovic & Igor Filipcic, 2016. "Psychological Symptoms in Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS): A Case Report," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 1(2), pages 40-42, September.
    • Handle: RePEc:adp:joajnn:v:1:y:2016:i:2:p:40-42
    DOI: 10.19080/OAJNN.2016.01.555559
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