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Congenital Zika Syndrome A Clinical Study of Six Patients

Author

Listed:
  • Orlando J Castejón
  • Torres Ytalo
  • Pedro Finol Parra
  • Patricia Galindez
  • Maria Salones Castejón
  • Grundbaum Esmeira

    (Department of Neuroscience, Zulia University, Venezuela)

Abstract

Six infant patients with microcephaly and neurodevelopmental disorders were studied from the clinical point of view exhibiting mainly reduced cephalic circumference, spastic paralysis of upper and lower extremities, ostetendinous hiperreflexia, bilateral strabismus, dysmorphic faciee and genu valgo bilateral. Transfontanelar ecography showed thin and porous aspect of corpus callosum, and ventricolomegaly. Computerized axial tomography showed lissencephaly and calcifications in basal ganglia and dispersed in the thick and condensed brain parenchyma. Nuclear magnetic resonance neuroimages showed ventriculomegaly, absence of corpus callosum, scarce differentiation of gray and white matter, and vascular and cerebellar hypoplasia. Electroencephalographic recording displayed focal paroxysmal activity and hipsarritmia in some patients. Mothers were infected in the first and second trimester of pregnancy.

Suggested Citation

  • Orlando J Castejón & Torres Ytalo & Pedro Finol Parra & Patricia Galindez & Maria Salones Castejón & Grundbaum Esmeira, 2019. "Congenital Zika Syndrome A Clinical Study of Six Patients," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 10(2), pages 26-30, March.
    • Handle: RePEc:adp:joajnn:v:10:y:2019:i:2:p:26-30
    DOI: 10.19080/OAJNN.2019.10.555782
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