IDEAS home Printed from https://ideas.repec.org/a/adp/jnapdd/v5y2019i1p1-3.html
   My bibliography  Save this article

Theoretical Approaches for Treatment of Neglected Tropical Diseases by Drug Designed Gold Complexes with Thiosemicarbazone

Author

Listed:
  • Ronaldo Junio de Oliveira

    (Department of Physics, Institute of Exact, Natural Sciences and Education, Federal University of Triângulo Mineiro, Brazil)

Abstract

Theoretical studies have been increasing as a pivotal step in the design of novel compounds with biological activity. In special, molecular modeling and docking algorithms are computational tools used in the early stages of development and evaluation of drug candidates that may act in a specific biomolecule target. Regarding Chagas that is a neglected tropical disease, it has two enzymes which is used as major drug target: cruzain and Trypanosoma cruzi old yellow enzyme (TcOYE). In this manuscript, it will be reviewed the latest metal-based thiosemicarbazone compounds, specially gold(III), evaluated by theoretical tecniques for the discovery of new treatments for Chagas disease.

Suggested Citation

  • Ronaldo Junio de Oliveira, 2019. "Theoretical Approaches for Treatment of Neglected Tropical Diseases by Drug Designed Gold Complexes with Thiosemicarbazone," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 5(1), pages 1-3, March.
    • Handle: RePEc:adp:jnapdd:v:5:y:2019:i:1:p:1-3
    DOI: 10.19080/NAPDD.2019.05.555651
    as

    Download full text from publisher

    File URL: https://juniperpublishers.com/napdd/pdf/NAPDD.MS.ID.555651.pdf
    Download Restriction: no
    File URL: https://juniperpublishers.com/napdd/NAPDD.MS.ID.555651.php
    Download Restriction: no
    File URL: https://libkey.io/10.19080/NAPDD.2019.05.555651?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:adp:jnapdd:v:5:y:2019:i:1:p:1-3. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Robert Thomas (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.