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Erythrocyte as a Therapeutic Target

Author

Listed:
  • Carlota Saldanha
  • Ana Silva Herdade

    (Institute of Biochemistry, Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon. Portugal)

Abstract

Erythrocytes are powerful components of blood flow designed to scavenger or deliver nitic oxide (NO) and oxygen to all cells in the body and transport carbon dioxide from them to the lungs. Blood components started to be quantified and erythrocyte blood shapes used as diagnostic and prognostic tools in clinical practice. Erythrocytes have hemorheological, hemostatic and pro or anti-inflammatory properties enlarging their physiological implications in health and disease. As blood component the erythrocytes establish interaction with others white blood cells, platelets, plasma lipoproteins and vascular endothelial cells. The aim of this mini review is highlight the signaling pathway of nitric oxide in which some steps explain the efficacy of some therapeutic drugs already used and could point new targets for further application in inflammatory vascular diseases

Suggested Citation

  • Carlota Saldanha & Ana Silva Herdade, 2017. "Erythrocyte as a Therapeutic Target," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 2(3), pages 64-66, August.
    • Handle: RePEc:adp:jnapdd:v:2:y:2017:i:3:p:64-66
    DOI: 10.19080/NAPDD.2017.02.555590
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    References listed on IDEAS

    as
    1. Carlota Saldanha & António Messias, 2017. "Sepsis Needs Follow-Up Studies in Intensive Care Units- Another Avenue for Translational Research," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 1(1), pages 12-14, May.
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    Cited by:

    1. Carlota Saldanha, 2020. "Therapeutic Approach for Covid-19 Patients," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 5(3), pages 55-57, September.
    2. Carlota Saldanha & Ana Silva Herdade, 2018. "Erythrocyte Acetylcholinesterase is a Signaling Receptor," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 3(4), pages 77-80, January.

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