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In-vitro and In-silico Drug-Food Interaction: an Evaluation of Metformin and Green Tea Interactions

Author

Listed:
  • Obiuwevbi O Daniel
  • Jacob A Kolawole

    (Department of Pharmaceutical Chemistry, University of Jos, Nigeria)

  • Olanike C Kolawole

    (Department of Pharmaceutical and Medicinal Chemistry, Kaduna state University, Nigeria)

Abstract

Food-drug interaction is a consequence of physical, chemical or physiological relationship between a drug and food. Failure to identify and properly manage food-drug interaction can lead to serious consequences such as reduction in absorption of certain orally administered drugs thereby leading to failure of treatments. This study sort to explore the effect of green tea on Metformin uses both in-vitro dissolution test and in-silico docking interactions models.

Suggested Citation

  • Obiuwevbi O Daniel & Jacob A Kolawole & Olanike C Kolawole, 2017. "In-vitro and In-silico Drug-Food Interaction: an Evaluation of Metformin and Green Tea Interactions," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 2(2), pages 34-39, June.
    • Handle: RePEc:adp:jnapdd:v:2:y:2017:i:2:p:34-39
    DOI: 10.19080/NAPDD.2017.02.555584
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    References listed on IDEAS

    as
    1. Jerzy Jankun & Steven H. Selman & Rafal Swiercz & Ewa Skrzypczak-Jankun, 1997. "Why drinking green tea could prevent cancer," Nature, Nature, vol. 387(6633), pages 561-561, June.
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