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Landscaping of Quinoline based Heterocycles as Potential Antimicrobial Agents: A Mini Review

Author

Listed:
  • Nisheeth C Desai
  • Bonny Y Patel
  • Krunalsinh A Jadeja

    (Division of Medicinal Chemistry, Department of Chemistry (DST-FIST Sponsored & UGC NON-SAP), Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar-364002, India)

  • Bharti P Dave

    (Department of Life Sciences, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, India)

Abstract

In this mini-review, we have compiled our research group’s prior efforts aimed at developing potential, novel and safe antimicrobial agents with improved efficiency by using the hybrid molecular approach on quinoline hybrids. Present mini-review article deals with landscaping of quinoline based bioactive analogues with pyrazoles, thiazoles, 4-thiazolidinones, pyrimidines and 2-pyridones heterocycles. Quinoline motifs containing hybrids with two or more fold antimicrobial activity are described hereby. We have reported a mini review of 174 compounds prepared in our laboratory. The SAR of the most promising compounds is also discussed.

Suggested Citation

  • Nisheeth C Desai & Bonny Y Patel & Krunalsinh A Jadeja & Bharti P Dave, 2017. "Landscaping of Quinoline based Heterocycles as Potential Antimicrobial Agents: A Mini Review," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 1(4), pages 64-67, June.
  • Handle: RePEc:adp:jnapdd:v:1:y:2017:i:4:p:64-67
    DOI: 10.19080/NAPDD.2017.01.555570
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