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Bioactive Compound Produced from Actinomycetes- Streptomyces

Author

Listed:
  • Parisa Azerang
  • Soroush Sardari

    (Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Pasteur Institute of Iran, Tehran)

Abstract

The beginning of antibiotic-resistance among the bacteria is really unavoidable. Over the last 60 years, bacteria and, in particular, those pathogenic for humans have evolved toward anti-microbial drug resistance. For the treatment of infectious diseases antibiotics like penicillin and erythromycin are used but now these antibiotics become less effective because bacteria have become more resistant to such antibiotics. The development of new antimicrobial agents is an urgent medical need. Natural products are important sources of lead antimicrobial agents. Actinomycetes are soil dwelling and Gram positive bacteria and industrially wide range of bioactive secondary metabolites producers, including many antibiotics. More than75% of antibiotics are sourced from the genus Streptomyces. This review article focuses on microbial secondary metabolites from Streptomyces as new drugs to fight against antibiotic resistance.

Suggested Citation

  • Parisa Azerang & Soroush Sardari, 2017. "Bioactive Compound Produced from Actinomycetes- Streptomyces," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 1(3), pages 52-53, June.
    • Handle: RePEc:adp:jnapdd:v:1:y:2017:i:3:p:52-53
    DOI: 10.19080/NAPDD.2017.01.555565
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