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Appraisal of In-Vitro Antimicrobial, Thrombolytic and Membrane Stabilizing Potentials of Chloroform Extract of Avicennia Marina Leaves and Barks: An Approach to Develop Novel Drug

Author

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  • Md. Shalahuddin Millat
  • Md. Saddam Hussain
  • Mohammad Nurul Amin
  • Md. Ibrahim
  • Farhana Sultana

    (Lignin Valorization & Nanomaterials Lab, University of the Punjab, Pakistan)

Abstract

ByThe present study was aimed to assess ethno medicinal value of the plant. We tried to oversee in-vitro antimicrobial, thrombolytic and membrane stabilizing potentials of chloroform extracts of Avicennia marina leaves and barks. A. marina is an ethno medicinal plant belongs to the family of Acanthaceae. Crude chloroform extracts of A. marina (leaves & barks) dose dependently used for in vitro antimicrobial, thrombolytic and membrane stability screening. Chloroform extracts of A. marina at higher concentration evolved moderate antimicrobial activities against Gram negative (-ve) bacteria and were resistant against Gram positive (+ve) bacteria during assessment through disc diffusion method. During analysis of thrombolytic activity, 10mg/ml concentration of the extracts most significantly showed 16.33±0.49% lysis of clot (p

Suggested Citation

  • Md. Shalahuddin Millat & Md. Saddam Hussain & Mohammad Nurul Amin & Md. Ibrahim & Farhana Sultana, 2017. "Appraisal of In-Vitro Antimicrobial, Thrombolytic and Membrane Stabilizing Potentials of Chloroform Extract of Avicennia Marina Leaves and Barks: An Approach to Develop Novel Drug," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 1(2), pages 32-37, May.
    • Handle: RePEc:adp:jnapdd:v:1:y:2017:i:2:p:32-37
    DOI: 10.19080/NAPDD.2017.01.555560
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