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Retropharyngeal, Mediastinal, Retroperitoneal Edema A Rare Presentation of Angiotensin Converting Enzyme Inhibitor (ACEI) Induced Angioedema

Author

Listed:
  • Muhammad Umer Butt MDMS

    (Department of Cardiology, Metrohealth Medical Center, USA)

  • Ahmad Jabri MD

    (Department of Internal Medicine, Akron General Cleveland Clinic, USA)

  • Samy Claude Elayi MD

    (Department of Internal Medicine, Ambulatory Care Center, USA)

Abstract

Angioedema is a scarce and potentially life-threatening complication of angiotensin converting enzyme (ACE) inhibitor use. ACE inhibitors previously were noted to cause oropharyngeal and airway edema. Visceral edema involving the gastrointestinal tract was previously seen occasionally. We present here a rare case of retropharyngeal, prevertebral, retroperitoneal edema related to ACE inhibitor use that has not been documented before. The patient presented with throat soreness with changes in his voice. Computed tomography showed edema within the hypopharynx, prevertebral soft tissue extending to the upper mediastinum, and even down to retroperitoneum. The laboratory work was within normal limits, ruling out acquired, hereditary or allergic/immunologic type of angioedema. All clinical symptoms resolved immediately with lisinopril discontinuation without any other therapy.

Suggested Citation

  • Muhammad Umer Butt MDMS & Ahmad Jabri MD & Samy Claude Elayi MD, 2019. "Retropharyngeal, Mediastinal, Retroperitoneal Edema A Rare Presentation of Angiotensin Converting Enzyme Inhibitor (ACEI) Induced Angioedema," JOJ Internal Medicine, Juniper Publishers Inc., vol. 1(1), pages 15-16, June.
    • Handle: RePEc:adp:jjojim:v:1:y:2019:i:1:p:15-16
    DOI: 10.19080/JOJIM.2019.01.555553
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