IDEAS home Printed from https://ideas.repec.org/a/adp/jjojdc/v2y2020i4p46-48.html
   My bibliography  Save this article

Pretibial Myxedema, Nodular Variant: Unique Presentation and Clinical Course

Author

Listed:
  • Rand Abou Shaar
  • Shereen Zia
  • Mohamed Alhamar
  • Adrian Ormsby

    (Department of Pathology and Laboratory Medicine, Henry Ford Health System, Detroit, USA)

Abstract

Literature has shown morphological diversity in the presentation and occurrence of pretibial myxedema following I-131 treatment. We present a case of a 47 y.o African American male with post I-131 hypothyroidism for Graves disease that presented with enlarging bilateral lower extremity and ankle lesions. Examination revealed firm, tender, hemispherical, large, hyperpigmented nodules. Ultrasound demonstrated nonspecific hypovascular nodular thickening of the skin. Excisional biopsy showed reactive dermal and subcutaneous fibrosis with dermal mucinosis. Alcian blue stain confirmed the diagnosis. Graves’ dermopathy is generally rare, with the nodular variant accounting for 10% of cases. Our case reflects a variable appearance of post-I-131 treatment dermopathy partially resistant to the multimodal treatment.

Suggested Citation

  • Rand Abou Shaar & Shereen Zia & Mohamed Alhamar & Adrian Ormsby, 2020. "Pretibial Myxedema, Nodular Variant: Unique Presentation and Clinical Course," JOJ Dermatology & Cosmetics, Juniper Publishers Inc., vol. 2(4), pages 46-48, April.
    • Handle: RePEc:adp:jjojdc:v:2:y:2020:i:4:p:46-48
    DOI: 10.19080/JOJDC.2020.02.555591
    as

    Download full text from publisher

    File URL: https://juniperpublishers.com/jojdc/pdf/JOJDC.MS.ID.555591.pdf
    Download Restriction: no
    File URL: https://juniperpublishers.com/jojdc/JOJDC.MS.ID.555591.php
    Download Restriction: no
    File URL: https://libkey.io/10.19080/JOJDC.2020.02.555591?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:adp:jjojdc:v:2:y:2020:i:4:p:46-48. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Robert Thomas (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.