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Improvement in Scalp Dermatomyositis with Platelet-Rich Plasma

Author

Listed:
  • Hosking AM
  • Margit Juhász
  • Chloe Ekelem

    (Department of Dermatology, University of California, USA)

  • Junxiao Yu
  • Emon Heidari

    (University of California, Irvine, Beckman Laser Institute, USA)

  • Jeffrey Rapaport
  • Zhongping Chen
  • Mesinkovska NA

    (Cosmetic Skin and Surgery Center, Englewood Cliffs, USA)

Abstract

Dermatomyositis (DM) is an inflammatory myopathy with hallmark cutaneous findings, including heliotrope rash, Gottron’s papules, as well as photodistributed erythema and/or poikiloderma. Scalp DM (SDM) presents as erythematous plaques with overlying scale, associated with severe burning pruritus. Due to inflammation, it may also present with non-scarring alopecia. First-line treatment for SDM includes intralesional corticosteroids; however, to date, no therapy has proven effective. Platelet-rich plasma (PRP) is an emerging treatment modality for a variety of disease entities including arthritis, oral surgery, and skin rejuvenation. Recent reports demonstrate PRP may have a promising role in hair regrowth. Herein, we report a case of refractory SDM with significant clinical improvement after treatment with subdermal PRP injections of the scalp. We also used optical coherence tomography (OCT) as a non-invasive imaging methodology to longitudinally monitor hair growth over the 18-week PRP treatment interval.

Suggested Citation

  • Hosking AM & Margit Juhász & Chloe Ekelem & Junxiao Yu & Emon Heidari & Jeffrey Rapaport & Zhongping Chen & Mesinkovska NA, 2018. "Improvement in Scalp Dermatomyositis with Platelet-Rich Plasma," JOJ Dermatology & Cosmetics, Juniper Publishers Inc., vol. 1(3), pages 45-48, October.
    • Handle: RePEc:adp:jjojdc:v:1:y:2018:i:3:p:45-48
    DOI: 10.19080/JOJDC.2018.01.555562
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