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Treatment of Diabetic Retinopathy (DR) and Diabetic Macular Edema (DME)

Author

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  • George Chiou CY

    (Texas A&M University Health Science Center Houston,USA
    Director of New Drug R&D CenterNatureWise Biotech and Medicals Corp, Taiwan)

Abstract

The worldwide prevalence of diabetic retinopathy (DR) is at a staggeringly high level, 127 M patients in 2010 and will grow to 191 M by 2030. It is a leading cause of blindness in working-age populations [1]. Obviously, an ideal potent and safe drug is urgently needed for its treatment. However, none is available despite utmost efforts have been made by numerous research institutions. Current treatment of DR includes anti-VEGF for angiogenesis suppression; intravitreal steroid injection for inflammation inhibition; laser surgery for stopping vascular leakage; and vitrectomy for hypoxia [2-5]. None of these treatments are ideal as they are invasive in delivery and disliked by patients. Besides, VEGF is an essential ingredient for normal formation and function of blood vessels and thus a complete elimination with VEGF inhibitors could cause serious adverse effects, whereas steroid injection causes systemic side effects which are resisted by both patients and doctors. Thus, even though various means are available, there is only one, VEGF inhibitors, that is preferentially used at the present time.

Suggested Citation

  • George Chiou CY, 2018. "Treatment of Diabetic Retinopathy (DR) and Diabetic Macular Edema (DME)," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 5(5), pages 126-127, July.
    • Handle: RePEc:adp:jgjpps:v:5:y:2018:i:5:p:126-127
    DOI: 10.19080/GJPPS.2018.05.555674
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