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A Concise Review on Microspheres for Targeted Drug Delivery

Author

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  • Bissera Pilicheva

    (Department of Pharmaceutical Sciences, Medical University-Plovdiv, Bulgaria)

Abstract

In recent years, there has been a growing number of studies demonstrating that microspheres have a strong potential for selective drug delivery and highlighting the ability to target these carriers to different parts of the body using sophisticated delivery technologies. Microspheres are solid, spherical particles of 1-1000μm in size, most often made of a polymer matrix in which the active substance is dispersed at molecular or macroscopic level. The use of mucoadhesive polymers for the construction of the polymer matrix leads to the formation of particles prone to prolonged retention of the applied site-mucoadhesive microspheres Siepmann [1]. Although micro carriers might be used for targeted delivery of drugs in different therapeutic areas, the need for precise selective introduction of drug molecules into targeted tissues and organs is perhaps of greatest significance in the treatment of oncological diseases.

Suggested Citation

  • Bissera Pilicheva, 2018. "A Concise Review on Microspheres for Targeted Drug Delivery," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 5(2), pages 73-76, April.
    • Handle: RePEc:adp:jgjpps:v:5:y:2018:i:2:p:73-76
    DOI: 10.19080/GJPPS.2018.05.555664
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