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Bilateral Mastectomy for Breast Cancer Prevention

Author

Listed:
  • Leah Whitman
  • Kaitlyn Champion
  • Casey Clark
  • Adegoke Adeniji

    (South University, School of Pharmacy, USA)

Abstract

Breast cancer continues to be a major public health concern and cause of female mortality despite significant advancements in prevention methods. Surprisingly, regardless of the abundance of evidence supporting other methods of prevention, twice as many women are choosing bilateral mastectomy. Several trials have investigated the efficacy of removing healthy breast tissue to prevent cancer development and recurrence, yet such procedures remain controversial. Breast cancer recurrence, disease-free survival, cost-effectiveness, and quality of life post-surgery are critical components of a patient’s decision to undergo prophylactic bilateral mastectomy. Selection of an appropriate prevention method requires an accurate and complete understanding of each available option. Here we review the current evidence concerning the use of bilateral mastectomy for breast cancer prevention, and compare the choice of undergoing the procedure to other less invasive prevention methods such as chemoprevention, which remains the gold standard for breast cancer prevention.

Suggested Citation

  • Leah Whitman & Kaitlyn Champion & Casey Clark & Adegoke Adeniji, 2018. "Bilateral Mastectomy for Breast Cancer Prevention," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 4(4), pages 82-93, february.
  • Handle: RePEc:adp:jgjpps:v:4:y:2018:i:4:p:82-93
    DOI: 10.19080/GJPPS.2018.04.555643
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