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Chagas Disease: A Neglected Disease

Author

Listed:
  • Mohemmed Faraz Khan
  • Wasim Akhtar
  • Mohammad Shaquiquzzaman
  • Garima Verma
  • Mohammad Mumtaz Alam

    (Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, India)

  • Sarwat Tauhid
  • Syed Rashiduddin

    (Department of Chemistry, Oriental College, India)

Abstract

Chagas disease or American trypanosomiasis is a neglected disease caused by Trypanosoma cruzi and spread by insects ‘triatomine’ or ‘kissing bugs’. Once, this disease was completely confined to the region of Latin America, but has now spread to different regions of the world due to immigration. Around 6 to 7 million people across the world are affected with this infection. This disease presents itself in two phases: acute and chronic, each with its own characteristic features. Various diagnostic techniques are available to confirm this infection. Benznidazole and nifurtimox are clinically used to relive the infected patients. Both these have 100% efficacy, if given soon after infection at the onset of acute phase. However, both of them are associated with some limitations, thereby necessitating the need for novel and safe agents.

Suggested Citation

  • Mohemmed Faraz Khan & Wasim Akhtar & Mohammad Shaquiquzzaman & Garima Verma & Mohammad Mumtaz Alam & Sarwat Tauhid & Syed Rashiduddin, 2017. "Chagas Disease: A Neglected Disease," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 3(3), pages 55-57, July.
    • Handle: RePEc:adp:jgjpps:v:3:y:2017:i:3:p:55-57
    DOI: 10.19080/GJPPS.2017.03.555612
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