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Systemic Lupus Erythematous Emergence in a Multiple Sclerosis Patient Treated with Fingolimod

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  • Amir Neshatfar

    (Multiple Sclerosis and Neuro-Immunology Research Center, Isfahan University of medical sciences, Iran)

Abstract

Fingolimod (FIN) is a novel therapy in multiple sclerosis with some side effects. There have been some studies in which the potential risk of consequent exacerbation of autoimmune diseases after use of fingolimod has been discussed. According to our knowledge our study is the only one investigating a case of fingolimod causing systemic lupus erythematous. We report a case of multiple sclerosis with no history of any rheumatologic disorder who experienced arthritis within two weeks after initiation of fingolimod therapy, which can be a potential consequence of dysregulation of immune system and its impact on regulatory T cells. Finally we concluded that fingolimod therapy can potentially cause autoimmune disorders in patients with clear history of such diseases.

Suggested Citation

  • Amir Neshatfar, 2017. "Systemic Lupus Erythematous Emergence in a Multiple Sclerosis Patient Treated with Fingolimod," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 2(5), pages 110-112, June.
    • Handle: RePEc:adp:jgjpps:v:2:y:2017:i:5:p:110-112
    DOI: 10.19080/GJPPS.2017.02.555600
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