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C-Peptide-Boon or Bane in Diabetes

Author

Listed:
  • Eerike M
  • Konda VGR
  • Rajamanickam MK

    (Department of Pharmacology, Chettinad Hospital & Research Institute, India)

Abstract

Chronic hyperglycemia in diabetes will produce microvascualr & macrovascular complications. Strict glycemic control can reduce but not completely prevent the microvascular complications. C-peptide, a connecting peptide is one of the drugs under clinical trials for treatment of diabetic complications. Previously C-peptide was considered as a byproduct of insulin synthesis, but now it has been proven, as an active hormone with various actions. Replacement with C-peptide has been proven to reduce the type-1 diabetic complications but not in type 2 diabetic complications. This review is focusing on mechanism of action and actions of C-peptide, its role in type1 & type 2 diabetic complications, clinical trials related to C-peptide has been discussed.

Suggested Citation

  • Eerike M & Konda VGR & Rajamanickam MK, 2017. "C-Peptide-Boon or Bane in Diabetes," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 2(1), pages 12-14, May.
    • Handle: RePEc:adp:jgjpps:v:2:y:2017:i:1:p:12-14
    DOI: 10.19080/GJPPS.2017.02.555578
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