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Cannabinoids in Autism and Fragile X Syndrome: Value-Based Treatment Revolution Ahead?

Author

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  • Zoran M Pavlovic

    (Independent CNS Consultant and CEO Neuroscience and Mental Health Services, Serbia)

Abstract

Cannabis has a long history in Central and South Asia, as it was used to produce hemp fibre for rope, clothing and paper, but was also consumed both for recreational and medicinal purposes. The two major neuro active components in cannabis are the psychoactive Δ9-tetrahydro-cannabinol (Δ9-THC) and the non-psychoactive cannabidiol (CBD). Recent years have seen a resurgence in interest in the therapeutic potential of compounds derived from cannabis, due to significant advances in our understanding of cannabis ingredients and endogenous brain cannabinoid (ECB) system, which consists of G-protein-coupled cannabinoid (CB) receptors, endocannabinoids such as N-Arachidonoylethanolamide (Anandamide) and 2-Arachidonoylglycerol (2-AG), synthetic and degradative enzymes, and transporters.

Suggested Citation

  • Zoran M Pavlovic, 2017. "Cannabinoids in Autism and Fragile X Syndrome: Value-Based Treatment Revolution Ahead?," Global Journal of Intellectual & Developmental Disabilities, Juniper Publishers Inc., vol. 3(1), pages 1-4, September.
    • Handle: RePEc:adp:jgjidd:v:3:y:2017:i:1:p:1-4
    DOI: 10.19080/GJIDD.2017.03.555601
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