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Promoter Hypermethylation of Apoptotic

Author

Listed:
  • Bader A Abdelmaksoud

    (Clinical oncology, Oncologist, King Abdulaziz Specialist Hospital, Aljouf, KSA)

  • Zaki Alalem

    (Lecturer of clinical oncology, Faculty of medicine, Zagazig university, Egypt)

  • Fayez G Alruwaily

    (Consultant family medicine and palliative care physician, King Abdulaziz Specialist Hospital, Aljouf, KSA)

  • Ahmad A Dafaallah

    (Urologist, King Abdulaziz Specialist Hospital, Aljouf, KSA)

Abstract

Diagnosis of prostate cancer is suspected if there are abnormalities during digital rectal examination (DRE) and/or steady rising in levels of prostate specific antigen (PSA) and the confirmative diagnosis is established by histopathological confirmation of malignancy by biopsy from the prostate. In this report, 87 years old male diagnosed clinically (DRE), radiologically and biochemically (markedly elevated PSA level) as a case of advanced prostate cancer and started treatment without biopsy. After one month of treatment and then after, the quality of life of the patient was significantly improved, and within 7 months patient showed radiologically and biochemically complete response, so, treatment of advanced prostate cancer might be started without biopsy if there is high probabilities malignancy in exceptional cases

Suggested Citation

  • Bader A Abdelmaksoud & Zaki Alalem & Fayez G Alruwaily & Ahmad A Dafaallah, 2019. "Promoter Hypermethylation of Apoptotic," Cancer Therapy & Oncology International Journal, Juniper Publishers Inc., vol. 13(5), pages 109-112, May.
    • Handle: RePEc:adp:jctoij:v:13:y:2019:i:5:p:109-112
    DOI: 10.19080/CTOIJ.2019.13.555873
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