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Nanoparticles as Biomarkers and Biosensors

Author

Listed:
  • Anchal Srivastava
  • R K Shukla
  • Nishant Kumar
  • Anu Katiyar

    (Department of Physics, University of Lucknow, India)

Abstract

Biomarker, a measurable indicator of some biological state or condition, has journeyed for better from organic fluorescencent substances to chalcogenide quantum dots to biocompatible metal oxide semiconductor nano particles. Single-band up-conversion nanoparticles have been realized doing away with any kind of spectral interference with the living cell autoflourescence. Zinc oxide based thin films and nanostructures have shown striking performance due to its high isoelectric point and other multifunctional characteristics besides non toxic nature to in vivo applications. Rare earth doped ZnO and ZnAl2O4 nanoparticles can be used as biomarkers. Also, nanomaterials such as nanoparticles, nanorods, nanowires, etc. offer large surface to volume ratio and therefore they can offer high sensitivity. Added with the advanced nanofabrication techniques ZnO based portable biosensors will not remain a dream but still a lot of diligence is required to achieve the target.

Suggested Citation

  • Anchal Srivastava & R K Shukla & Nishant Kumar & Anu Katiyar, 2017. "Nanoparticles as Biomarkers and Biosensors," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 9(3), pages 43-46, September.
    • Handle: RePEc:adp:jctbeb:v:9:y:2017:i:3:p:43-46
    DOI: 10.19080/CTBEB.2017.09.555762
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    References listed on IDEAS

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    1. Yang Shen & Jianhua Zhou & Tianran Liu & Yuting Tao & Ruibin Jiang & Mingxuan Liu & Guohui Xiao & Jinhao Zhu & Zhang-Kai Zhou & Xuehua Wang & Chongjun Jin & Jianfang Wang, 2013. "Plasmonic gold mushroom arrays with refractive index sensing figures of merit approaching the theoretical limit," Nature Communications, Nature, vol. 4(1), pages 1-9, December.
    2. Robert M. Dickson & Andrew B. Cubitt & Roger Y. Tsien & W. E. Moerner, 1997. "On/off blinking and switching behaviour of single molecules of green fluorescent protein," Nature, Nature, vol. 388(6640), pages 355-358, July.
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