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Modern Methods of Bioengineering in Production of Probiotics

Author

Listed:
  • Murat Zh Nurushev

    (L.N. Gumilyov Eurasian National University, Astana, Kazakhstan)

  • Lidia G Stoyanova

    (M.V. Lomonosov Moscow State University, Moscow, Russia)

Abstract

Physiological and biochemical features of new strains were studied and compared to the nisin-producing strain Lactococcus lactis ssp. lactis MSU. According to morphological, cultural, physiological, biochemical properties and gene sequence of 16S rRNA a novel most effective strain 194 was identified as Lactococcus lactis ssp. lactis (GenBank database DQ 255954), absolutely harmless for human health and animals. We studied the probiotic properties, sensitivity to antibiotics and show the therapeutic effect of strain as a food additive on model mice CBRB-Rb 1Iem chronic dermatitis. Thus, the properties of the strain 194, such as wide spectrum action to the pathogenic species and medical effect in a mouse model of chronic dermatitis enable to recommend the strain L. lactis ssp. lactis 194 for using as probiotic culture.

Suggested Citation

  • Murat Zh Nurushev & Lidia G Stoyanova, 2017. "Modern Methods of Bioengineering in Production of Probiotics," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 5(3), pages 77-84, June.
    • Handle: RePEc:adp:jctbeb:v:5:y:2017:i:3:p:77-84
    DOI: 10.19080/CTBEB.2017.05.555666
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