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Anti-Evolutionary Targets in Bacterial Efflux Pumps Future Therapeutics to Combat Antibacterial Resistance

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  • Pavan Gollapalli

    (Department of PG studies and Research in Biotechnology and Bioinformatics, Kuvempu University, India)

Abstract

The global emergence of multi-drug resistance in the pathogenic bacteria is a growing threat to antibiotic therapy. One of the major contributions to antibiotic resistance was by efflux mechanisms in the bacteria and they present a major challenge for antibiotic development. Hence, comprehensive understanding of the drug resistance mechanisms that are adopted by the regulation and physiological functions of efflux pumps at systems level. In this review, by attempt to present a brief outline to develop anti-evolutionary drugs to combat antibacterial resistance in most of the pathogens.

Suggested Citation

  • Pavan Gollapalli, 2017. "Anti-Evolutionary Targets in Bacterial Efflux Pumps Future Therapeutics to Combat Antibacterial Resistance," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 1(5), pages 109-110, February.
  • Handle: RePEc:adp:jctbeb:v:1:y:2017:i:5:p:109-110
    DOI: 10.19080/CTBEB.2017.01.555575
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    References listed on IDEAS

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    1. Christopher Walsh, 2000. "Molecular mechanisms that confer antibacterial drug resistance," Nature, Nature, vol. 406(6797), pages 775-781, August.
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