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Neurobehioural Effects of Chronic Consumption of Uncooked Black Eye Beans on Spatial Learning and Memory in Mice

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  • Aduema W

    (Department of Human Physiology, Gregory University, Nigeria)

Abstract

Beans, the stable diet of Nigerians contains serotonin and its precursor, 5-Hydroxytryptophan. Serotonin as a neurotransmitter has neurobehavioural actions which include mood, memory, learning and sleep. It was therefore the aim of this study to find out whether long term consumption of uncooked black eye beans (Vigna unguiculata) diet commonly called iron beans, has effects on some neurobehavioural parameters notably; learning and memory, using Swiss white mice as experimental animals. Thirty (30) CD1 mice weighing 18-30g were randomly assigned into three groups, viz; control, uncooked beans and serotonin precursor. They were fed normal rodent chow and 50% uncooked beans diet (w/w), while another set of mice were placed on serotonin precursor (5-HTP) diet (0.2mg/50g w/w) respectively for four weeks.

Suggested Citation

  • Aduema W, 2016. "Neurobehioural Effects of Chronic Consumption of Uncooked Black Eye Beans on Spatial Learning and Memory in Mice," Current Trends in Biomedical Engineering & Biosciences, Juniper Publishers Inc., vol. 1(2), pages 27-31, December.
    • Handle: RePEc:adp:jctbeb:v:1:y:2016:i:2:p:27-31
    DOI: 10.19080/CTBEB.2016.01.555556
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    Cited by:

    1. Nomso C & Aduema W, 2018. "Effects of Ethanol Extract Leaves of nymphaea lotus (water lily) on Learning and Memory in CD-1 Mice," Global Journal of Pharmacy & Pharmaceutical Sciences, Juniper Publishers Inc., vol. 4(3), pages 55-62, January.

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