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In Vivo Screening of the Extract of Solenostemon Monstachyus and Ocimum Gratissimum for the Management of Type-2 Diabetes

Author

Listed:
  • Ikpesu TO

    (Department of Biology, Federal University Otuoke, Nigeria)

  • Ezenwaka CO

    (Department of Biology, Federal University Otuoke, Nigeria)

Abstract

The efficacy of synergistic of Solenostemon monostachyus and Ocimum gratissimum for the management of type-2-diabetes using Zebra fish was investigated. The plants were dried, grounded and the powder was pooled together, homogenized and extracted for 7 hours using the Soxhlet apparatus. A total of 75 zebra fish were used and were divided into five groups of five juveniles per test concentration in three replicates. Group A was given de-chlorinated water; B was treated with 0.25mg/L diazinon only while other groups were exposed to the same concentration as in group B, but with different concentrations of the plant’s extract. Group C, D and E received 250, 500 and 750mg/L respectively.

Suggested Citation

  • Ikpesu TO & Ezenwaka CO, 2018. "In Vivo Screening of the Extract of Solenostemon Monstachyus and Ocimum Gratissimum for the Management of Type-2 Diabetes," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 7(5), pages 99-103, July.
    • Handle: RePEc:adp:jcrdoj:v:7:y:2018:i:5:p:99-103
    DOI: 10.19080/CRDOJ.2018.07.555723
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    Keywords

    juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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