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Studies on Glucagon Receptor and Antagonists of Glucagon Receptor for the Management of Diabetes Mellitus

Author

Listed:
  • Ghulam Abbas

    (Department of Biological Sciences and Chemistry, University of Nizwa, Oman
    Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Oman)

  • Ahmed Al Harrasi

    (Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Oman)

  • Hidayat Hussain

    (Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Oman)

Abstract

Glucagon receptor plays an important role in the glucose homeostasis and thus is drug target for the management of hyperglycemia in type-2 diabetes mellitus. The suppression of glucagon secretion from the alpha-cells is the key to control hyperglycemic condition. The identification of non-peptide antagonists of glucagon receptor is an effective therapeutic approach to inhibit the glucagon secretion to achieve normal glucose index.

Suggested Citation

  • Ghulam Abbas & Ahmed Al Harrasi & Hidayat Hussain, 2018. "Studies on Glucagon Receptor and Antagonists of Glucagon Receptor for the Management of Diabetes Mellitus," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 5(4), pages 76-78, January.
    • Handle: RePEc:adp:jcrdoj:v:5:y:2018:i:4:p:76-78
    DOI: 10.19080/CRDOJ.2018.05.555667
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    Keywords

    juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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