IDEAS home Printed from https://ideas.repec.org/a/adp/jcrdoj/v11y2019i1p18-27.html
   My bibliography  Save this article

Effects of Spironolactone About Vascular Inflammation on a Metabolic Syndrome Model

Author

Listed:
  • Nicolas F Renna

    (Department of Pathology, School of Medicine, National University of Cuyo, IMBECU-CONICET, Argentina
    Centro Integrativo de Biología y Química Aplicada (CIBQA), Universidad Bernardo OHiggins, Santiago, Chile)

  • Rodrigo D Garcia

    (Department of Pathology, School of Medicine, National University of Cuyo, IMBECU-CONICET, Argentina)

  • Jesica M Ramirez

    (Genetics Institute, School of Medicine, National University of Cuyo, Argentina)

  • Roberto M Miatello

    (Department of Pathology, School of Medicine, National University of Cuyo, IMBECU-CONICET, Argentina)

Abstract

Background: Aldosterone (A) has pro-oxidative, pro-growth and pro-inflammatory effects in different tissues. We have previously demonstrated that in vascular inflammation different cytokines as NF-kB and VCAM-1 were present and generated a proinflammatory microenvironment that supports this cardiovascular remodeling. We proposed to evaluate the effects of spironolactone (S) antagonist mineralocorticoid receptor (MR) about vascular remodeling in metabolic syndrome model.

Suggested Citation

  • Nicolas F Renna & Rodrigo D Garcia & Jesica M Ramirez & Roberto M Miatello, 2019. "Effects of Spironolactone About Vascular Inflammation on a Metabolic Syndrome Model," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 11(1), pages 18-27, June.
    • Handle: RePEc:adp:jcrdoj:v:11:y:2019:i:1:p:18-27
    DOI: 10.19080/CRDOJ.2019.11.555804
    as

    Download full text from publisher

    File URL: https://juniperpublishers.com/crdoj/pdf/CRDOJ.MS.ID.555804.pdf
    Download Restriction: no
    File URL: https://juniperpublishers.com/crdoj/CRDOJ.MS.ID.555804.php
    Download Restriction: no
    File URL: https://libkey.io/10.19080/CRDOJ.2019.11.555804?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Nicolas F Renna & Rodrigo D Garcia & Jesica M Ramirez & Roberto M Miatello, 2019. "Effects of Spironolactone About Vascular Inflammation on a Metabolic Syndrome Model," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 11(1), pages 1-10, June.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Nicolas F Renna & Rodrigo D Garcia & Jesica M Ramirez & Roberto M Miatello, 2019. "Effects of Spironolactone About Vascular Inflammation on a Metabolic Syndrome Model," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 11(1), pages 1-10, June.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      More about this item

      Keywords

      juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
      All these keywords.

      JEL classification:

      • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
      • Z0 - Other Special Topics - - General

      Statistics

      Access and download statistics

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:adp:jcrdoj:v:11:y:2019:i:1:p:18-27. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Robert Thomas (email available below). General contact details of provider: .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.