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Research Progress of Transcription Factor KLF4 in Lung Cancer

Author

Listed:
  • Minjun Dong

    (Department of Surgical Oncology, Zhejiang University School of Medicine, China)

  • Liang Luo

    (Department of Gastroenterology, Zhejiang University School of Medicine, China)

  • Yunlu Jia

    (Zhejiang University School of Medicine, China)

  • Xianqiu Lu

    (Zhejiang University School of Medicine, China)

  • Yongcheng Liu

    (Department of Surgical Oncology, Zhejiang University School of Medicine, China)

  • Yuan s

    (Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China)

Abstract

Lung cancer is the leading cause of cancer mortality worldwide. While our understanding of the molecular events in the lung cancers are poor. In this report, we reviewed the current studies on a transcription factor named Krüppel-like Factor 4(KLF4) in lung cancer. Tissue studies showed that KLF4 expression was significantly decreased in non-small-cell lung cancer (NSCLC), while significant over expression in small-cell lung cancer (SCLC).

Suggested Citation

  • Minjun Dong & Liang Luo & Yunlu Jia & Xianqiu Lu & Yongcheng Liu & Yuan s, 2017. "Research Progress of Transcription Factor KLF4 in Lung Cancer," International Journal of Pulmonary & Respiratory Sciences, Juniper Publishers Inc., vol. 1(5), pages 139-142, June.
    • Handle: RePEc:adp:ijoprs:v:1:y:2017:i:5:p:139-142
    DOI: 10.19080/IJOPRS.2017.01.555575
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