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Evaluation of the Cytotoxicity and Anticytotoxicity of Brugmansia Suaveolens in Mus Musculus Mice

Author

Listed:
  • Mateus Silva Santos
  • Maria Alice Montes de Souza
  • Lucas Rodrigues Sampaio

    (Department of Biotechnological Experiments, Laboratory of the Pontifical Catholic University of Goiás, Brazil)

  • Paulo Roberto de Melo-Reis

    (Department of Genetic, Laboratory (LaGene) of the Pontifical Catholic University of Goiás (PUC-GO), Brazil)

Abstract

Someone individuals search through alternative sources for substances that provide hallucinogenic effects, changes in mood and perception. The Brugmansia suaveolens, a plant commonly found in Brazil, is widely used, whether in religious cults and indigenous tribes. This plant has the ability to interact with the central nervous system inducing potent hallucinogenic effects to the user. However, there are few studies evaluating the toxicological risk of this plant. The present study aimed to evaluate possible cytotoxic / anticytotoxic activities based on the PCE/NCE ratio of hematopoietic bone marrow of mice.

Suggested Citation

  • Mateus Silva Santos & Maria Alice Montes de Souza & Lucas Rodrigues Sampaio & Paulo Roberto de Melo-Reis, 2019. "Evaluation of the Cytotoxicity and Anticytotoxicity of Brugmansia Suaveolens in Mus Musculus Mice," International Journal of Cell Science & Molecular Biology, Juniper Publishers Inc., vol. 6(3), pages 108-111, November.
    • Handle: RePEc:adp:ijcsmb:v:6:y:2019:i:3:p:108-111
    DOI: 10.19080/IJCSMB.2019.06.555694
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