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Dedifferentiated Chondrosarcoma of the Larynx A Case Report and Review of the Literature

Author

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  • Kelsey C Hinther

    (College of Medicine, University of Saskatchewan, Canada)

  • Rick Jaggi

    (Division of Otolaryngology, University of Saskatchewan, Canada)

Abstract

Laryngeal chondrosarcomas are rare, slow-growing, cartilaginous tumors. Dedifferentiated chondrosarcomas, a rare entity of chondrosarcoma, are more aggressive and associated with a more ominous prognosis. Definite diagnosis can be established by incisional biopsy and histopathologic examination. Histopathologic examination reveals a cartilaginous tumor with a malignant spindle cell component. Definitive reatment of dedifferentiated chondrosarcomas of the larynx is total laryngectomy. There have been 14 case reports of laryngeal dedifferentiated chondrosarcoma reported since 1988. The average life expectancy reported is 6 months, and a 5-year survival rate of 10.5%.

Suggested Citation

  • Kelsey C Hinther & Rick Jaggi, 2018. "Dedifferentiated Chondrosarcoma of the Larynx A Case Report and Review of the Literature," International Journal of Cell Science & Molecular Biology, Juniper Publishers Inc., vol. 4(2), pages 25-31, March.
    • Handle: RePEc:adp:ijcsmb:v:4:y:2018:i:2:p:25-31
    DOI: 10.19080/IJCSMB.2018.03.555631
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