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Resistance of Human Endometrium to Ferroptosis

Author

Listed:
  • Namika Yoshida

    (Department of Human Health Sciences, Nutrition Science Course, University of Nagasaki, Japan)

  • Ayaka Tanaka
  • Kotoha Takaki

    (Department of Nutrition Science, Faculty of Nursing and Nutrition, University of Nagasaki, Japan)

  • Susumu Tanaka

    (Department of Human Health Sciences, Nutrition Science Course, University of Nagasaki, Japan
    Department of Nutrition Science, Faculty of Nursing and Nutrition, University of Nagasaki, Japan)

Abstract

Although iron is an essential nutrient, ferroptosis (cell death) occurs in response to excess iron. Iron-induced lipid peroxidation damages to cell membranes and leads to cell death. Menstruation, on the other hand, is a peri- odic expulsion of blood and detached endometrium (menstrual blood). Some of the endometrium remains after menstruation, exposed to high concentrations of blood-derived iron, however re-proliferates and undergoes de- cidualization, an essential differentiation for embryo implantation.

Suggested Citation

  • Namika Yoshida & Ayaka Tanaka & Kotoha Takaki & Susumu Tanaka, 2024. "Resistance of Human Endometrium to Ferroptosis," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 59(3), pages 51673-51679, November.
    • Handle: RePEc:abf:journl:v:59:y:2024:i:3:p:51673-51679
    DOI: 10.26717/BJSTR.2024.59.009318
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    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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