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Letter to the Editor Regarding the NLR Member CIITA- Master Controller of Adaptive and Intrinsic Immunity and Unexpected tool in Cancer Immunotherapy

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  • Zheng long Liu

    (School of Preclinical Medicine and Forensic Medicine, North Sichuan Medical College, China)

Abstract

We read the article by Greta Forlani and Mariam Shallak, who introduced the NLR member CIITA as an unexpected tool for assessing adaptive and intrinsic immunity and cancer immunotherapy [1]. CIITA is a founding member of the NLR protein family [2]. The regulation of MHC-II gene expression is largely regulated at the CIITA and MHC-II levels, so it is critical to regulate MHC-II gene expression. This paper reveals the use of CIITA as a tool for inducing MHC-II gene and molecular expression in tumor cells, opening new possibilities for improving the recognition and characterization of tumor antigens and imaging realistic antitumor vaccine strategies.

Suggested Citation

  • Zheng long Liu, 2023. "Letter to the Editor Regarding the NLR Member CIITA- Master Controller of Adaptive and Intrinsic Immunity and Unexpected tool in Cancer Immunotherapy," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 54(2), pages 45722-45723, December.
  • Handle: RePEc:abf:journl:v:54:y:2023:i:2:p:45722-45723
    DOI: 10.26717/BJSTR.2023.54.008523
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