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Atherosclerotic Background of Cirrhosis in Sickle Cell Diseases

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  • Mehmet Rami Helvaci

    (Specialist of Internal Medicine, MD, Turkey)

Abstract

The hardened RBCs-induced capillary endothelial damage initiates at birth and terminates with multiorgan failures even at childhood. Parallel to cirrhosis, all of the atherosclerotic risk factors or consequences including smoking, alcohol, disseminated teeth losses, ileus, COPD, leg ulcers, digital clubbing, CHD, CRD, and stroke were higher, and auto splenectomy and mean age of mortality were lower in males which cannot be explained by effects of smoking and alcohol alone at the relatively younger mean age. So auto splenectomy may be a good whereas male gender alone may be a bad prognostic factor, and cirrhosis may have an atherosclerotic background in the SCDs.

Suggested Citation

  • Mehmet Rami Helvaci, 2023. "Atherosclerotic Background of Cirrhosis in Sickle Cell Diseases," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 54(1), pages 45304-45317, December.
    • Handle: RePEc:abf:journl:v:54:y:2023:i:1:p:45304-45317
    DOI: 10.26717/BJSTR.2023.54.008481
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