IDEAS home Printed from https://ideas.repec.org/a/abf/journl/v53y2023i1p44207-44216.html
   My bibliography  Save this article

Research on the Molecular Mechanism of Combination Triptolide with Dexamethasone in Treatment of Rheumatoid Arthritis based on Bioinformatics Analysis

Author

Listed:
  • Lianbo Xiao

    (Institute of Arthritis Research in Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, China)

Abstract

Triptolide (TP), a diterpenoid triepoxide from Tripterygium wilfordii Hook F, can ameliorate rheumatoid arthritis (RA) through multiple molecular mechanisms. However, serious side effects limit its clinic application. Previous studies have shown that combination of TP with dexamethasone (DXM) had the synergetic effect, but the mechanism is still unknown. Therefore, this study aims to investigate the molecular mechanism of combination TP with DXM in the treatment of rheumatoid arthritis by bioinformatics analysis.

Suggested Citation

  • Lianbo Xiao, 2023. "Research on the Molecular Mechanism of Combination Triptolide with Dexamethasone in Treatment of Rheumatoid Arthritis based on Bioinformatics Analysis," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 53(1), pages 44207-44216, September.
    • Handle: RePEc:abf:journl:v:53:y:2023:i:1:p:44207-44216
    DOI: 10.26717/BJSTR.2023.53.008331
    as

    Download full text from publisher

    File URL: https://biomedres.us/pdfs/BJSTR.MS.ID.008331.pdf
    Download Restriction: no
    File URL: https://biomedres.us/fulltexts/BJSTR.MS.ID.008331.php
    Download Restriction: no
    File URL: https://libkey.io/10.26717/BJSTR.2023.53.008331?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:abf:journl:v:53:y:2023:i:1:p:44207-44216. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Angela Roy (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.