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Kinetics of α2-Macroglobulin in Rats with GentamicinInduced Acute Severe Renal Failure

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  • Takashi Kuribayashi

    (Laboratory of Immunology, School of Life and Environmental Science, Azabu University, Japan)

Abstract

The kinetics of α2-macroglobulin (α2M) were evaluated in rats with acute severe renal failure. This renal failure was induced by repeated subcutaneous injections of gentamicin at a dose of 80 or 120 mg/kg for 10 days. Twenty-two male Sprague-Dawley rats were divided into two groups for two experiments. Turpentine oil was intramuscularly injected at a dosage of 0.2 mL/kg body weight at 2 days after finishing the injections of gentamicin. The serum concentrations of α2M were then measured by enzyme-linked immunosorbent assay.

Suggested Citation

  • Takashi Kuribayashi, 2023. "Kinetics of α2-Macroglobulin in Rats with GentamicinInduced Acute Severe Renal Failure," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 52(5), pages 44038-44043, September.
    • Handle: RePEc:abf:journl:v:52:y:2023:i:5:p:44038-44043
    DOI: 10.26717/BJSTR.2023.52.008301
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