IDEAS home Printed from https://ideas.repec.org/a/abf/journl/v52y2023i4p43887-43896.html
   My bibliography  Save this article

The Cytotoxicity of Metformin and Misoprostol Overwhelms their Antiviral Activity in SARS-CoV-2-Infected Vero-E6 Cell Culture

Author

Listed:
  • Sherine Abdelmissih

    (Department of Medical Pharmacology, Faculty of Medicine, Kasr Al-Ainy, Cairo University, Cairo, Egypt)

Abstract

Coronavirus disease 2019 (COVID-19) due to the acute respiratory syndrome coronavirus2 (SARS-CoV-2) caused a global health crisis that called for re-purposing of many medications. Both the implication of diabetes mellitus (DM) in increasing the risk of COVID-19-associated respiratory complications, together with the claims about the involvement of acidic pH in exacerbating acute lung injury as well as SARS-CoV-2 invasion, growth, and replication, guided our interest towards possible efficacy of antidiabetic and anti-peptic ulcer medications in such condition.

Suggested Citation

  • Sherine Abdelmissih, 2023. "The Cytotoxicity of Metformin and Misoprostol Overwhelms their Antiviral Activity in SARS-CoV-2-Infected Vero-E6 Cell Culture," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 52(4), pages 43887-43896, August.
    • Handle: RePEc:abf:journl:v:52:y:2023:i:4:p:43887-43896
    DOI: 10.26717/BJSTR.2023.52.008281
    as

    Download full text from publisher

    File URL: https://biomedres.us/pdfs/BJSTR.MS.ID.008281.pdf
    Download Restriction: no
    File URL: https://biomedres.us/fulltexts/BJSTR.MS.ID.008281.php
    Download Restriction: no
    File URL: https://libkey.io/10.26717/BJSTR.2023.52.008281?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:abf:journl:v:52:y:2023:i:4:p:43887-43896. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Angela Roy (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.