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High Urinary Nitric Oxide Levels May Indicate the Presence of Bladder Outlet Obstruction, But Not Overactive Bladder

Author

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  • Kimio Sugaya

    (Southern Knights’ Laboratory, Okinawa, Japan)

Abstract

Nitric oxide (NO) exerts multiple biological actions and is one of the most crucial signaling molecules [1,2]. It is endogenously synthesized from the precursor L-arginine by a family of NO synthases (neuronal [nNOS], inducible [iNOS], and endothelial NO synthase [eNOS]), with stoichiometric production of L-citrulline. NO activates soluble guanylyl cyclase in cells to synthesize cyclic guanosine monophosphate (cGMP) and relax smooth muscle.

Suggested Citation

  • Kimio Sugaya, 2023. "High Urinary Nitric Oxide Levels May Indicate the Presence of Bladder Outlet Obstruction, But Not Overactive Bladder," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 52(4), pages 43826-43831, August.
    • Handle: RePEc:abf:journl:v:52:y:2023:i:4:p:43826-43831
    DOI: 10.26717/BJSTR.2023.52.008271
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