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The Aging Brain- Impact of Iron Metal in Neurotoxicity

Author

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  • Khadga Raj Aran

    (DNeuroscience Division, Department of Pharmacology, ISF College of Pharmacy (An Autonomous College), Moga, Punjab, India)

Abstract

Critical changes in cellular and molecular processes that occur with ageing disturb the central nervous system’s homeostatic equilibrium. Metal accumulation makes the brain more vulnerable to neurotoxic shocks through mechanisms such mitochondrial failure, calcium-ion dyshomeostasis in neurons, a buildup of damaged molecules, reduced DNA repair, decreased neurogenesis, and impaired energy metabolism.

Suggested Citation

  • Khadga Raj Aran, 2023. "The Aging Brain- Impact of Iron Metal in Neurotoxicity," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 52(3), pages 43742-43746, August.
    • Handle: RePEc:abf:journl:v:52:y:2023:i:3:p:43742-43746
    DOI: 10.26717/BJSTR.2023.52.008255
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