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Clinical Application of Mesenchymal Stem Cells for Cancer Therapy- A Review of Registered Clinical Trials

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  • Tuong Thi Van Thuy

    (Tuong Thi Van Thuy, Stem Cell Center, Phu San Ha Noi Hospital, Vietnam)

Abstract

Mesenchymal stem cells (MSCs) were discovered in the 1970s with their unique properties of differentiation, immunomodulation, multiple secreting, and homing factors to injured organs. MSC-based therapies have emerged as a promising strategy for various diseases such as cancer, tissue regeneration, or immunologic/ inflammatory-related diseases. This study evaluated the clinical application of MSCs for cancer therapy in trials registered on ClinicalTrial.gov as of July 2022. The results showed 40 clinical trials used MSCs in various cancer conditions. 62% of trials used MSCs for therapeutic purposes to minimize the side effects of cancer treatment.

Suggested Citation

  • Tuong Thi Van Thuy, 2023. "Clinical Application of Mesenchymal Stem Cells for Cancer Therapy- A Review of Registered Clinical Trials," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 51(5), pages 43196-43121, July.
    • Handle: RePEc:abf:journl:v:51:y:2023:i:5:p:43196-43121
    DOI: 10.26717/BJSTR.2023.51.008178
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