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Diisononyl Phthalate Perturbs Immune Cell Energy Transduction by Disrupting Some Splenic and Lymphocyte Energy Metabolising Enzymes Activities

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  • Abosede Temitope Olajide

    (Department of Biomedical Science, Faculty of Medicine, and Health Science, Universiti, Putra, Malysia)

Abstract

Energy homeostasis is a hallmark of cell survival and maintenance of cell function, some cell types (e.g., immune cells such as the spleen and lymphocyte) have special functions that demand energy over and above the basic rate (e.g., for antigen processing and presentation, migration and phagocytosis). Independently of the amount of energy needed by cells or the kind of nutrients they metabolize to generate energy, the immediate donor of free energy is mainly represented by adenosine-5’-triphosphate (ATP). The effect of diisononyl phthalate (DiNP) on splenic and lymphocyte energy metabolism was examined.

Suggested Citation

  • Abosede Temitope Olajide, 2023. "Diisononyl Phthalate Perturbs Immune Cell Energy Transduction by Disrupting Some Splenic and Lymphocyte Energy Metabolising Enzymes Activities," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 51(4), pages 42860-42865, July.
    • Handle: RePEc:abf:journl:v:51:y:2023:i:4:p:42860-42865
    DOI: 10.26717/BJSTR.2023.51.008127
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