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Liver Function Status of Diabetic Wistar Rats Treated with Ethanol Extract of Cucumis Sativus Fruit

Author

Listed:
  • Abu OD

    (Department of Biochemistry, Faculty of Life Sciences, University of Benin, Nigeria)

Abstract

Diabetes mellitus is a fast growing metabolic disorder and one of the leading causes of death worldwide. The aim of this study was to evaluate the effect of ethanol extract of Cucumis sativus on liver function in diabetic rats. Adult male Wistar albino rats (n = 25) weighing 200 to 230 g (mean weight = 215 ± 15 g) were used for this study. The rats were randomly assigned to five groups of 5 rats each: normal control group, diabetic control group, metformin group, 200 mg/kg bwt extract and 300 mg/kg bwt extract groups.

Suggested Citation

  • Abu OD, 2023. "Liver Function Status of Diabetic Wistar Rats Treated with Ethanol Extract of Cucumis Sativus Fruit," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 51(2), pages 42440-42445, June.
    • Handle: RePEc:abf:journl:v:51:y:2023:i:2:p:42440-42445
    DOI: 10.26717/BJSTR.2023.51.008065
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    References listed on IDEAS

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    1. David E. Moller, 2001. "New drug targets for type 2 diabetes and the metabolic syndrome," Nature, Nature, vol. 414(6865), pages 821-827, December.
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    Cited by:

    1. Abu OD, 2023. "Ethanol Extract of C. Sativus Modulates the Activity of Glucose 6-Phosphatase/ Aminotransferases and Levels of Lipids in Tissues of STZ-Induced Diabetic Rats," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 53(4), pages 44989-44994, November.
    2. Abu OD, 2023. "Protective Property of Ethanol Extract of C. Sativus on STZ-Induced Diabetic Rat Pancreas," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 52(2), pages 43613-43618, August.
    3. Abu OD & Awhin EP & Ohikhuare F & Osamudiamen EE, 2024. "Investigation of the Biochemical Effect of Aqueous Extract of Dialium guineense Stem Bark on Haematological Parameters in Rats," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 58(1), pages 49990-49997, August.
    4. Abu OD & Umar AB & Ekperusi SE & Ohikhuare F, 2024. "Assessment of Cardiac Oxidative Status of Diabetic Wistar Rats Exposed to Methanol Fraction of Ethanol Extract of Dialium Guineense Stem Bark," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 57(2), pages 49002-49009, June.
    5. Abu OD & Awhin EP & Iyoha AI & Chukwuma AU, 2024. "Hepatotoxicity of Aqueous Extract of Dialium Guineense Stem Bark in Rats," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 55(2), pages 46902-46907, February.

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      JEL classification:

      • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
      • Z0 - Other Special Topics - - General

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