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Wnt Signaling- A Boon or Bane for Alzheimer’s Disease

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  • Suborno Jati

    (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States)

Abstract

Alzheimer’s disease (AD) is the most abundant form of dementia worldwide and elderly people are prone to this disease. Until now, no such therapeutic intervention has been identified to curb it. Wnt signaling being a major regulator of systemic homeostasis, plays a significant role in the disease response. Wnt signaling pathway is intrinsically associated with the regulation of synaptic plasticity, microglial activation and maintenance of blood brain barrier (BBB). In spite of these all-round executions, there is a lack of detailed study to present an opinion about the importance of this signaling cascade in AD. In this review we will uphold the major queries related to the disease which can be elucidated by Wnt signaling pathway.

Suggested Citation

  • Suborno Jati, 2023. "Wnt Signaling- A Boon or Bane for Alzheimer’s Disease," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 51(1), pages 42275-42279, June.
  • Handle: RePEc:abf:journl:v:51:y:2023:i:1:p:42275-42279
    DOI: 10.26717/BJSTR.2023.51.008045
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