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Usefulness of the Acute Phase Reactants (APR) Score [Part 3]- Mechanism of Increase in Acute Phase Reactants by Evaluating Cytokine Profiles; Haptoglobin is Associated with Increased Iterleukin-6 Promoted by Interleukin-1β

Author

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  • Toshihiko Nakamura

    (Department of Neonatology, Japanese Red Cross Musashino Hospital, Japan)

Abstract

Neonatal bacterial infection is diagnosed when the acute phase reactants score (APR-Sc) is positive for 3 items of CRP, α1-acid glycoprotein (AGP), and haptoglobin (Hp), and 2 points are positive for 2 items, CRP and AGP. However, the mechanism by which the presence or absence of an increase in Hp, which is the difference between the 3 points and the 2 points, is not known.

Suggested Citation

  • Toshihiko Nakamura, 2023. "Usefulness of the Acute Phase Reactants (APR) Score [Part 3]- Mechanism of Increase in Acute Phase Reactants by Evaluating Cytokine Profiles; Haptoglobin is Associated with Increased Iterleukin-6 Prom," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(5), pages 42118-42125, June.
  • Handle: RePEc:abf:journl:v:50:y:2023:i:5:p:42118-42125
    DOI: 10.26717/BJSTR.2023.50.008024
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