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Some Indicators of Intoxication and Leukocyte Response in Rodent Fecal Peritonitis

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  • EV Husakouskaya

    (Department of Pathophysiology named after D A Maslakov, Grodno State Medical University, Belarus)

Abstract

The experiments were carried out on male rats (n=74), divided into 2 equal series, which were injected intraperitoneally with: 1st series (control) – 0,9% sodium chloride, 2nd series (experimental peritonitis, EP) – 15 % fecal suspension, 0,6 ml/100 g. Studies were made after half a day (n=6), one day (n=6) and three days (n=6) of EP, lethality of animals also was assessed (n=19). In rats with fecal peritonitis, some indicators of intoxication were studied by assessing of motor activity, muscle strength, respiration rate and rectal temperature, and the reaction of blood and peritoneal leukocytes basing on determining their quantitative composition and phagocytic activity.

Suggested Citation

  • EV Husakouskaya, 2023. "Some Indicators of Intoxication and Leukocyte Response in Rodent Fecal Peritonitis," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 50(5), pages 42055-42060, June.
    • Handle: RePEc:abf:journl:v:50:y:2023:i:5:p:42055-42060
    DOI: 10.26717/BJSTR.2023.50.008012
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